It was claimed Suri, who celebrated her 18th birthday in April, was the beneficiary of trusts set up by both the Top Gun star and Holmes, who were married from 2006 to 2012.
The Dawson's Creek alum, 45, took to social media to shut down the rumours about her daughter's net worth, claiming the reports posed a safety threat to her only child.
Writing on Instagram, Holmes deplored the "completely false" report and told TheDaily Mail "you can stop making stuff up".
The actor further emphasised her annoyance by adding the caption "enough". She also interacted with the comment section and agreed with users who claimed such stories "should be against the law".
Holmes and Cruise welcomed their daughter Suri in April 2006. The actors first met in 2005 and were engaged two months later, before they tied the knot in an Italian ceremony in November 2006.
Holmes later filed for divorce from the Eyes Wide Shut star in June 2012 after five years of marriage.
The First Daughter star has previously opened up about keeping her daughter safe because of her childhood in the spotlight.
"What has been really important for me with my daughter, because she was so visible at a young age, is I really like to protect her," she told Glamour in April 2023.
"I'm very grateful to be a parent, to be her parent. She's an incredible person."
However, the Batman Begins star still confessed that she's asked Suri to be involved in every project she works on.
Holmes even enlisted her daughter to sing "Blue Moon" during the opening credits of her 2022 film, Alone Together. Suri also sang in her mother's 2023 movie, Rare Objects.
"I hope she always does something on my films. I always ask her," she explained.
"But both of those experiences came out of the same sense of what I love about our industry, which is, you have these projects and you become a family with people. And it's this safe, beautiful, creative space."
She continued: "So it comes out of love for me to include someone who I love dearly. That's how I like to work. I like to have that kind of feeling.
"It was very meaningful to me to have her there, because she's my heart."